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Accelerating the Discovery of Monoclonal Antibodies (mAbs) and T-cell Receptors (TCRs) using Lab on a Particle Technology

Conference Presentation

Keynote Speaker: Dr. Dino Di Carlo, Armond and Elena Hairapetian Professor of Bioengineering at UCLA

Presented at: SLAS 2024

“Lab on a particle” technologies, such as Nanovials, are emerging as an accessible platform for performing single-cell functional screening leveraging standard instrumentation, such as flow cytometers and microfluidic single-cell sequencing platforms. Each cell and its secreted products can be analyzed and sorted using widely available fluorescence activated cell sorters operating at up to a 1000 cells per second, promising to democratize single-cell discovery efforts. The Nanovial platform enables sorting cells based on secreted products for the discovery of high affinity antibodies, the development of cell lines producing recombinant products, and the selection of functional cells for cell therapies. Learn about our progress in using Nanovial particles for discovery of monoclonal antibodies and the characterization and discovery of antigen-specific and metabolite-specific T cells. 

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December 13

Antibody Engineering & Therapeutics 2023

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March 20

Applying Nanovial Technology to Discover Rare T Cell Receptors