Publications
Function-first Discovery of High Affinity Monoclonal Antibodies Using Nanovial-Based Plasma B Cell Screening
Dilip Challa, Joseph de Rutte, Cassady Konu, Shreya Udani, Jesse Liang, Patrick J Krohl, Ronald Rondon, Kent Bondensgaard, Dino Di Carlo, Jennifer Watkins-Yoon
bioRxiv, August 2024
Lab on a Particle Technologies
Rajesh Ghosh, Alyssa Arnheim, Mark van Zee, Lily Shang, Citradewi Soemardy, Rui-Chian Tang, Michael Mellody, Sevana Baghdasarian, Edwin Sanchez Ochoa, Shun Ye, Siyu Chen, Cayden Williamson, Amrith Karunaratne, and Dino Di Carlo
Analytical Chemistry, May 2024
Optimizing Cell Therapy by Sorting Cells with High Extracellular Vesicle Secretion
Doyeon Koo, Xiao Cheng, Shreya Udani, Sevana Baghdasarian, Dashuai Zhu, Junlang Li, Brian Hall, Natalie Tsubamoto, Shiqi Hu, Jina Ko, Ke Cheng & Dino Di Carlo
Nature Communications, 2024
On the Compatibility of Single-Cell Microcarriers (Nanovials) with Microfluidic Impedance Cytometry
Cristian Brandi, Adele De Ninno, Filippo Ruggiero, Emanuele Limiti, Franca Abbruzzese, Marcella Trombetta, Alberto Rainer, Paolo Bisegna, and Federica Caselli.
Lab on a Chip, May 2024
Defining T cell receptor repertoires using nanovial-based binding and functional screening
Doyeon Koo, Zhiyuan Mao, Robert Dimatteo, Miyako Noguchi, Natalie Tsubamoto, Jami McLaughlin, Wendy Tran, Sohyung Lee, Donghui Cheng, Joseph de Rutte, Giselle Burton Sojo, Owen N. Witte & Dino Di Carlo
PNAS, March 2024
Associating growth factor secretions and transcriptomes of single cells in nanovials using SEC-seq
Shreya Udani, Justin Langerman, Doyeon Koo, Sevana Baghdasarian, Brian Cheng, Simran Kang, Citradewi Soemardy, Joseph de Rutte, Kathrin Plath & Dino Di Carlo
Nature Nanotechnology, December 2023
SEC-seq: Association of molecular signatures with antibody secretion in thousands of single human plasma cells
Rene Yu-Hong Cheng, Joseph de Rutte, Cade Ellis Ito, Andee R. Ott, Lucie Bosler, Wei-Ying Kuo, Jesse Liang, Brian E Hall, David J Rawlings, Dino Di Carlo, Richard G. James
Nature Communications, June 2023
Single-cell sorting based on secreted products for functionally defined cell therapies
Hiromi Miwa, Robert Dimatteo, Joseph de Rutte, Rajesh Ghosh & Dino Di Carlo
Nature Microsystems & Nanoengineering, July 2022
Suspendable Hydrogel Nanovials for Massively Parallel Single-Cell Functional Analysis and Sorting
Joseph de Rutte, Robert Dimatteo, Maani M. Archang, Mark van Zee, Doyeon Koo, Sohyung Lee, Allison C. Sharrow, Patrick J. Krohl, Michael Mellody, Sheldon Zhu, James V. Eichenbaum, Monika Kizerwetter, Shreya Udani, Kyung Ha, Richard C. Willson, Andrea L. Bertozzi, Jamie B. Spangler, Robert Damoiseaux, and Dino Di Carlo
ACS Nano, March 2022
Scalable Fabrication and Use of 3D Structured Microparticles Spatially Functionalized with Biomolecules
Sohyung Lee, Joseph de Rutte, Robert Dimatteo, Doyeon Koo, and Dino Di Carlo
ACS Nano, November 2022
Sorting Single‐Cell Microcarriers Using Commercial Flow Cytometers
Joseph de Rutte, Robert Dimatte, Sheldon Zhu, Maani M. Archang, Dino Di Carlo
SLAS Technology, October 2021
Statistical Energy Minimization Theory for Systems of Drop-Carrier Particles
Ryan Shijie Du, Lily Liu, Simon Ng, Sneha Sambandam, Bernardo Hernandez Adame, Hansell Perez, Kyung Ha, Claudia Falcon, Joseph de Rutte, Dino Di Carlo, and Andrea L. Bertozzi
Physical Review E, July 2021
Monodisperse Drops Templated by 3D-Structured Microparticles
Chueh-Yu Wu, Mengxing Ouyang, Bao Wang, Joseph de Rutte, Alexis Joo, Matthew Jacobs, Kyung Ha, Andrea L. Bertozzi, Dino Di Carlo
Science Advances, November 2020