New Preprint: Association of Molecular Signatures with Antibody Secretion Using SEC-seq
Although researchers can currently tie gene expression signatures to the presence of surface proteins on a cell, there is a lack of tools to extend discoveries further, to what cells do. We sought to give researchers the power to answer these fundamental questions by developing SEC-seq, a new approach to link the secretions of individual cells to their underlying transcriptomes.
We are excited to announce the first (of many) publications on SEC-seq. In this work led by Richard James and Rene Chang from Seattle Children’s Hospital, the researchers explore the link between B cell secretion of IgG, surface markers and gene expression for thousands of single cells. The work was a collaboration with Dino Di Carlo, Brian Hall, and members of the Partillion Bioscience Team.
