News Update: Breakthrough Research in Immunoglobulin G (IgG) Production Featured in Nature Communications
August 14, 2023
A rendering of a plasma B cell secreting antibodies inside of a nanovial. (Image courtesy: Rene Chang/University of Washington).
We are thrilled to announce a groundbreaking development in Immunoglobulin G (IgG) research driven by a multi-institution collaboration between the Richard James Lab at Seattle Children’s Hospital, the Di Carlo Lab at UCLA, and our team at Partillion Bioscience. Our pioneering work has earned a spotlight in a recent article by UCLA and has been published in Nature Communications.
Using Partillion’s SEC-seq technology, the research teams successfully coupled the production of IgG with the underlying gene expression of human plasma B cells—a groundbreaking achievement that was previously unattainable. The insights gained from this study represent a significant advance in understanding plasma cell biology and hold the potential to catalyze the development of plasma cell-based therapies, an area in which the James' lab has been a pioneering force.
To learn more see the original articles below:
Nature Communications Article: https://www.nature.com/articles/s41467-023-39367-8
UCLA Article: https://newsroom.ucla.edu/releases/genes-linked-to-high-production-key-antibody